P05-01 Change in cardiorespiratory fitness in midlife and incident hypertension

Abstract Background Low cardiorespiratory fitness (CRF) is associated with higher blood pressure and risk of incident hypertension. However, existing literature has mainly investigated CRF at baseline. For HEPA initiatives, it is important to know how change in CRF in midlife associate with incident hypertension, and whether this varies between sexes, age and baseline CRF. Methods 91,728 individuals (20-79 years, 48% women, free from hypertension at baseline) from the Swedish workforce who had completed two health profile assessments in a nationwide occupational health service screening between 1986 and 2019 were included. CRF (assessed as VO2max) was estimated using a submaximal cycle test. Change in CRF between the two tests was expressed as % change in absolute CRF (L·min-1) per year and categorized as “maintainers” (-1% to 1% change/year), “decreases” (≥-1% change/year) or “increasers” (≥1% change/year). Incident hypertension was defined as having a blood pressure >140/90 mmHg or diagnosed with hypertension at the second test. Binary logistic regression was used to assess OR (95% CI) for hypertension at the second test between maintainers, decreases and increasers. All analyses were adjusted for sex, age, heart medication, time between tests, education, and change in other lifestyle variables between the two tests (stress, diet, exercise, smoking). Results Compared to maintainers (set as reference), OR for decreases was 1.27 (1.18-1.38) and increasers OR 0.99 (0.89-1.09). Isolating midlife participants (40-60 years), OR for decreasers was 1.47 (1.30-1.66) and increasers OR 0.75 (0.64-0.86). Looking at sex differences, male decreasers had OR 1.24 (1.12-1.36) and female decreasers OR 1.36 (1.20-1.56), compared to maintainers, while OR for male and female increasers was 0.93 (0.83-1.03) and 0.97 (0.83-1.13). For participants with low CRF at baseline (<32·kg-1·min-1), OR for decreasers was 1.70 (1.51-1.92) and increasers 1.32 (1.18-1.49). Corresponding ORs in those with high CRF at baseline were 0.90 (0.80-1.02) and 0.43 (0.26-0.71). Conclusions Decrease in CRF with >1% per year associated with significant higher risk for incident hypertension, while maintaining or increasing CRF had similar risk associations. This was seen in both men and women, different age-groups and baseline level of CRF. Health enhancing promotion strategies to maintain or increase CRF level is highly clinically relevant.

prevention of mobility disability in older adults with frailty and sarcopenia in 11 European countries, under the coordination of the Università Cattolica del Sacro Cuore, Italy. Altogether 1566 candidates were recruited to the SPRINtT RCT, and 142 of them in Finland.

Methods
The participants (n = 70) completed at least two years of physical activity training. The training was performed at moderate intensity and consisted of walking, strength, balance and flexibility exercises. The participants attended training two times a week at the center with the addition of home-based exercises. The training intensity increased gradually. The primary outcome of mobility disability was operationalized as an inability to complete the 400-m walk test. Secondary outcomes of physical performance were the short physical performance battery (SPPB) and handgrip strength.

Results
The results of the intervention will be revealed in spring 2020. Participants experienced that their physical performance improved during the follow-up. The physical activity program and the home-based exercises can be performed without any equipment and could, therefore, be easily implemented for practice.

Conclusions
The physical activity intervention was feasible and could be further recommended for older people with sarcopenia and Background One scope of the Active and Healthy Ageing framework is to increase awareness on elderly-related topics. The year 2020 has seen an upheaval across the world caused by the COVID-19 emergence, even higher to older persons.

Methods
In Italy, data gathered by the PASSI d'Argento behavioural surveillance system on general population aged 65+ in the timeframe 2016-2019 describe health conditions, lifestyles and care needs for elderly.

Results
Basing on physical activity recommended by the WHO globally, 33% of non-physically impaired older persons reaches out those levels, 27% are partially active, 40% is sedentary. 9% fell down within 30 days prior the interview, accessing hospital was necessary in 19% of cases; 64% of falling occurred at home, 20% outdoor. 61% refers at least one infrastructural housing issue, 15% perceive higher neighbourhood insecurity. 35% reported difficulties in accessing essential services, especially to local health premises and for necessities. About 19% lives socially isolated, 21% had not any contact (neither by phone) with anyone in a typical week, 71% do not attend collective meetings, such as at a club or church. Nearby 1 out of 3 (29%) represents an asset to the own family/community: 19% looks after cohabiting people, 14% relatives or friends not living together with, 6% engage in volunteering. Participation

Physical activity and health
Abstract citation ID: ckac095.068 P05-01 Change in cardiorespiratory fitness in midlife and incident hypertension Tobias Holmlund 1 , Bjö rn Ekblom 1 , Elin Ekblom-Bak 1 1 The Swedish School of Sport and Health Sciences, GIH, Å strand Laboratory of Work Physiology., Stockholm, Sweden Corresponding author: Tobias.holmlund@gih.se Background Low cardiorespiratory fitness (CRF) is associated with higher blood pressure and risk of incident hypertension. However, existing literature has mainly investigated CRF at baseline. For HEPA initiatives, it is important to know how change in CRF in midlife associate with incident hypertension, and whether this varies between sexes, age and baseline CRF. Methods 91,728 individuals (20-79 years, 48% women, free from hypertension at baseline) from the Swedish workforce who had completed two health profile assessments in a nationwide occupational health service screening between 1986 and 2019 were included. CRF (assessed as VO2max) was estimated using a submaximal cycle test. Change in CRF between the two tests was expressed as % change in absolute CRF (LÁmin-1) per year and categorized as ''maintainers'' (-1% to 1% change/year), ''decreases'' (!-1% change/year) or ''increasers'' (!1% change/year). Incident hypertension was defined as having a blood pressure >140/90 mmHg or diagnosed with hypertension at the second test. Binary logistic regression was used to assess OR (95% CI) for hypertension at the second test between maintainers, decreases and increasers. All analyses were adjusted for sex, age, heart medication, time between tests, education, and change in other lifestyle variables between the two tests (stress, diet, exercise, smoking).

Results
Compared to maintainers (set as reference), OR for decreases was 1. ORs in those with high CRF at baseline were 0.90 (0.80-1.02) and 0.43 (0.26-0.71). Conclusions Decrease in CRF with >1% per year associated with significant higher risk for incident hypertension, while maintaining or increasing CRF had similar risk associations. This was seen in both men and women, different age-groups and baseline level of CRF. Health enhancing promotion strategies to maintain or increase CRF level is highly clinically relevant. Keywords: Hypertension, cardiorespiratory, fitness, change, risk Abstract citation ID: ckac095.069 P05-02 Implementing exercise based injury prevention programs -lessons learned Joske Nauta 1 1 Public and Occupational Health, Amsterdam University Medical Center, Amsterdam, The Netherlands Corresponding author: j.nauta@amsterdamumc.nl

Background
In youth, physical activity is for a large part accumulated through participating in sports clubs and gymnastic classes. One of the reasons youth drop-out from sports and physical education participation are the injuries they sustain while being active. And, although we know that exercise based injury prevention programs can reduce the physical activity related injury risk, it has proven to be difficult to convince coaches, trainers and physical education teachers to implement these preventive exercises in their training/teaching routines. This presentation will focus on the lessons learned regarding the experiences and views of coaches, trainers and physical education teachers that participated in our injury prevention trials.

Background
The purpose of the study was to evaluate the role of physical exercises in improving cognitive functions in type 2 diabetes mellitus.

Methods
The study protocol was approved by an ethics committee and all patients signed an informed consent. We examined 204 patients with type 2 diabetes aged 61.7 AE 11.2 years (persons hospitalized in the endocrinology department of the clinics of the Siberian State Medical University, Tomsk). Blind double method patients were randomized into 2 groups: the main one was engaged in physical therapy and the control group (observation). The study was carried out in two stages: at the first visit, a clinical and psychological examination was conducted, which included the Montreal Cognitive Function Assessment Scale and the Diabetes-dependent Quality of Life Questionnaire; repeated clinical and psychological examination was carried out after rehabilitation after 6 months Results At the first stage the study revealed the presence of cognitive impairment in type 2 diabetes, mainly in tasks on visualconstructive skills, memory, attention and speech. These disorders were reduced after physical therapy (second stage) by 2.6 points (t = 0.01, p = 0.00006): visual-constructive skills (t = 0.0, p = 0.008), speech (t = 0.0, p = 0.005), abstraction (t = 0.0, p = 0.002) and memory (t = 0.0, p = 0.0007), no change in cognitive function occurred in the observation group. In terms of carbohydrate metabolism: the level of HbA1c decreased by 0.9%, fasting glycemia -by 1.6 mmol/L in main group, but increased by 0,1% of HbA1c and by 0,2 mmol/L of glycemia in the observation group (second stage) (t = 2.0, p = 0.000003; t = 3.0, p = 0.0008). Patients involved in physical therapy showed improvement in a larger number of parameters -leisure, travel, vacation, personal life, appearance, self-confidence, future confidence, financial situation, dependence, food choice, choice of drinks, total point (p > 0.05), when there was a decrease in points in the parameters of the control group.

Conclusion
During rehabilitation in patients with type 2 diabetes, there is have been associated to cardiovascular (CVD) morbidity and mortality. Routinely assessing the PA-level of patients being admitted to hospital has been proposed. The aim was to explore PA-level and SED among patients prior to cardiac ward admission and whether this can predict all-cause mortality. Methods A longitudinal observational study of patients with ischemic heart disease, heart failure, cardiac arrhythmia, valvular heart disorder and inflammatory heart diseases treated on cardiac wards (2015)(2016) in Stockholm, Sweden. Data on PA-levels and SED prior to admission were collected by validated questionnaires during inpatient care. PA level a regular week was calculated by an index (3-19 points) including everyday PA and exercise. The cut-off of insufficiently physically active was set to > 9 points. Individuals' reporting !7 hours of sitting a normal day were categorised as high SED. Differences in PAlevel and SED between different diagnose groups were